SAN DIEGO (AP) — LaMonte Wade Jr. singled over leaping All-Star shortstop Fernando Tatis Jr. in the ninth inning to bring in the go-ahead run and the San Francisco Giants beat the staggering San Diego Padres 6-5 Tuesday night to keep a one-game lead in the NL West.

Wade’s hit was the third straight one-out single off Mark Melancon (4-3) and brought in Brandon Belt. Melancon, who leads baseball with 37 saves, started the ninth with the score tied at 5.

The Giants stayed ahead of the Dodgers in the division race after Los Angeles beat Colorado 5-4.

The Padres blew a 4-1 lead and wasted a two-homer performance by Manny Machado three nights after his dugout dustup with Tatis. Machado came up with runners on first and second and one out in the ninth and grounded into a double play.

The Padres lost for the ninth time in 11 games, a skid that has dropped them from a one-game lead for the second wild-card spot to five games behind St. Louis, with Cincinnati a game ahead of them and Philadelphia a half-game ahead.

Padres right fielder Wil Myers made a great leaping catch to rob pinch-hitter Steven Duggar of a two-run homer to end the eighth and keep the game tied at 5.

Tatis added an RBI single for the Padres, whose chances at the second wild card were seriously damaged when they went 2-8 on a trip through Los Angeles, San Francisco and St. Louis.

Tony Watson (6-4) got the win and Tyler Rogers got his 13th save.

San Francisco rallied from a 4-1 deficit to take a 5-4 lead in the sixth against Joe Musgrove. Brandon Crawford doubled in Kris Bryant with the tying run and then scored the go-ahead run on Mike Yastrzemski’s sacrifice fly.

San Diego’s Austin Nola tied it with a homer off Zack Littell leading off the sixth.

The Giants started their comeback in the fifth when pinch-hitter Wilmer Flores had an RBI single and Buster Posey a sacrifice fly.

Tommy La Stella homered on Musgrove’s fifth pitch.

Both of Machado’s homers were off All-Star Kevin Gausman, who lasted only four innings, and both reached the Western Metal Supply Co. brick warehouse in the left-field corner. Machado homered with two outs in the first and leading off the third. It was his 30th career multihomer game and third this season. He has 26 homers this year.

Tommy Pham homered two batters later, his 15th, for a 4-1 lead. Tatis’ RBI single came in the second.

Gausman, who lost to the Padres on Thursday in San Francisco, allowed four runs and nine hits while striking out three and walking none.

Musgrove, who beat the Giants last Wednesday, allowed five runs and eight hits in 5 2/3 innings, struck out six and walked three.

It was in St. Louis in Saturday night that Machado shouted and cursed at Tatis during a face-to-face confrontation between the All-Stars. The dustup came after Tatis struck out looking and then argued the call by umpire Phil Cuzzi. Padres manager Jayce Tingler was ejected when he came out to argue on Tatis’ behalf.

Machado and Tatis stood next to each other after batting practice Tuesday and said all is well between them. Machado called Tatis “my little brother,” adding that the dugout blowup was unfortunate and happened due to the pressure of trying to win.

ROSTER MOVE

Padres: Designated RHP Jake Arrieta for assignment and reinstated RHP Javy Guerra from the 60-day injured list. The 35-year-old Arrieta was 0-3 with a 10.95 ERA in four starts with San Diego after being signed to a minor league contract following his release by the Chicago Cubs. He left Sunday’s start in St. Louis with a groin injury after getting just one out.

UP NEXT

LHP Scott Kazmir (0-1, 6.43) of the Giants and RHP Vince Velasquez (3-7, 6.09) of the Padres are scheduled to start Wednesday night.

___

More AP MLB: https://apnews.com/hub/MLB and https://twitter.com/AP_Sports