Panthers running back Christian McCaffrey did not practice Thursday, a sign that he could miss his third straight game while trying to rehab from a hamstring injury.

The 2019 All-Pro running back had participated in four straight practices for the Panthers on a limited basis.

Coach Matt Rhule told reporters on Wednesday that McCaffrey was “50-50” for the game and that his playing status would likely come down to a game-time decision. Rhule does not address reporters on Thursday of a normal game week.

The Panthers (3-2) host the Minnesota Vikings (2-3) on Sunday.

The Panthers’ 2017 first-round draft pick was injured in a Week 3 win against the Houston Texans. He hasn’t played since and the Panthers are 0-2 without him in the starting lineup after starting the season 3-0.

Chuba Hubbard would start if McCaffrey can’t play. Hubbard ran for 101 yards on 24 carries in Carolina’s 21-18 loss to the Philadelphia Eagles last Sunday.

The Panthers also placed punter Joe Charlton on injured reserve with back soreness and signed Ryan Winslow to the practice squad.

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Follow Steve Reed at https://twitter.com/SteveReedAP

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More AP NFL coverage: https://apnews.com/hub/NFL and https://twitter.com/AP_NFL

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