The NCAA Atlantic Regional hosted at Cooper Park begins with a clash of conference champions. No. 2-seeded Millersville won the PSAC Tournament, and No. 7 seed Charleston won a winner-take-all game with Glenville State to score its automatic berth to the NCAA Tournament. This marks the fourth regional match-up since 2018, and it is a reversal of roles from 2021 when Charleston played host to the regional.