There have been a few disappointing losses in the last three seasons, but which one takes the cake? Welcome to SB Nation Reacts, a survey of fans across the NCAA. Throughout the year we ask questions of the most plugged-in Missouri Tigers fans and fans across the country. Sign up here to participate. There is no easy way to sugar coat a loss like Missouri Football endured on Saturday. But was it the worst loss of the Drinkwitz era? Over the last three seasons there have been a handful of truly disappointing losses. There was the drubbing at Mississippi State…