The Jaguars head to Baltimore for a short-week matchup with a depleted Ravens team, but they’ll also be without nose tackle DaVon Hamilton, a key anchor of the NFL’s top-ranked run defense. Jacksonville’s priorities: find a way to contain Derrick Henry, capitalize on Baltimore’s quarterback absences and leave with a win—while the front office weighs defensive-line reinforcements before the trade deadline.

By the Numbers
  • Nov. 10: NFL trade deadline.
  • Hamilton: 6-foot-4, 335 pounds.
  • Jacksonville’s first Thursday Night Football appearance since October 2023.
Yes, But

Hamilton’s season-ending injury leaves a major gap, and no roster move is guaranteed: trades require a willing partner and must fit Jacksonville’s salary-cap and roster plans. Baltimore is missing Lamar Jackson and Tyler Huntley, but Henry and the Ravens’ defense still make this a dangerous road game.

State of Play
  • Defensive coordinator Anthony Campanile may need to adjust fronts and coverage to limit Henry without Hamilton.
  • Ruke Orhorhoro and Matt Dickerson could see increased roles as Jacksonville considers adding defensive-line help.
  • Rookie free agent Joe Fagnano is expected to start at quarterback for Baltimore.
  • Trevor Lawrence and head coach Liam Coen face an opportunity to deliver in prime time against rookie Ravens head coach Jesse Minter.
What's Next

Jacksonville faces Baltimore on Thursday, then has until the Nov. 10 deadline to pursue help at nose tackle or elsewhere on the defensive front. The game may hinge on Campanile’s plan against Henry and whether Lawrence can take advantage of Baltimore’s quarterback absences.

Bottom Line

For Jacksonville, this is a test of depth and adaptability: survive the short week, contain Henry and secure the win without risking the long-term roster for a rushed trade.