Oklahoma State hosts Colorado at 6 p.m. Saturday at Boone Pickens Stadium, looking to rebound from last week’s loss to Houston during America’s Greatest Homecoming. The Cowboys are favored by 13.5 points against a Colorado team that has lost four of its first six games.

By the Numbers
  • Oklahoma State is 4-2 overall and 2-1 in Big 12 play; Colorado is 2-4 and 0-3.
  • The Cowboys average 37.2 points and 517.7 yards per game; Colorado averages 19.5 points and 394.2 yards.
  • Oklahoma State quarterback Drew Mestemaker has thrown for 1,940 yards, 16 touchdowns and six interceptions.
  • The series stands at 27-20-1 in Colorado’s favor; the Buffaloes won the teams’ 2024 meeting, 52-0.
Yes, But

Oklahoma State has the stronger record and more productive offense, but Colorado leads the all-time series and shut out the Cowboys in their most recent meeting. Both teams also have players listed as out or questionable, including several Colorado wide receivers.

State of Play
  • The game airs on FS1 at 6 p.m. Saturday from Boone Pickens Stadium.
  • FanDuel lists Oklahoma State as a 13.5-point favorite, with a 56.5-point over/under.
  • Oklahoma State is tied for seventh in the Big 12 at 2-1; Colorado is winless in conference play.
Bottom Line

Oklahoma State has an opportunity to turn homecoming into a reset after its Houston loss—but Colorado’s recent blowout win in the series is a reminder that the Cowboys can’t rely on the odds alone.